Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, named COVID-19 (coronavirus disease 2019), represents an epoch-making global healthcare crisis, with more than 696.000 deaths caused to date (August 6, 2020) world wide. Although COVID19 may present as a multi-organ disease, the lung represents the most commonly affected target organ. Clinical manifestations may vary from flu-like symptoms, such as fever, dry cough, myalgia and fatigue, often coupled with hypo-/anosmia and ageusia, to more severe conditions with dyspnoea and respiratory impairment requiring admission to intensive care unit (ICU) and advanced respiratory assistance.

Download